You might have noticed that the cast list below shows "et al" as the roles for Mimi, Seth and Jerry.
They've not got it easy. Here's a sampling of the "et al" roles they are playing:
Mimi - Celia, dead Gus, Hooker, Liberty, Singer, Miss Certainty, Girl, Persephone
Seth - Giuseppe, EMT, Cop, Homeless Man, Old Man, Snowball Boy, Grafitti Boy, John, Rapist
Jerry - Alfonso, Harpist, Mouse, EMT, Priest, Businessman, Wino, Drug Dealer, Rat and corpse(s).
The role of Demeter, while not involving so many costume changes, has it's own challenges. You try sitting still for 45 minutes.